Tánaiste Leo Varadkar has said there is a "very good chance" that members of the public will be able to have domestic holidays this summer in a way that is similar to last year.
However, Mr Varadkar advised that anyone making bookings should make sure they are cancellable.
"I think we will be able to have beers outdoors with friends this summer and get around the country but you just never know because this virus has torn up our plans so many times," he said.
Speaking on RTÉ 2FM's Breakfast with Doireann and Eoghan, Mr Varadkar said he has a "home holiday" booked in Sligo for August.
"I think because of the vaccine and because of the change in the weather and because of what everyone is doing to get the virus down, I think there is a very good chance that this summer we will be able to have home holidays a bit like we did last summer," he said.
Mr Varadkar said the Government may have to change the order of which sections of the population get which vaccine but that a target of 70-80% of adults vaccinated by September was "doable".
"Because of the developments in the last couple of days, we will have to change the order of who gets which vaccine when, but we will still have the same number of vaccines in total," he said.
Meanwhile, Aontú leader Peadar Tóibín has said Taoiseach Micheál Martin should not travel to Washington for the annual Saint Patrick's Day celebrations if invited.
He said the Taoiseach would not be "leading by example" if he were to travel to the US while members of the public are being asked to limit their movements to a 5km radius.
Mr Tóibín told RTÉ's Today with Claire Byrne that the Taoiseach should instead invite the US President Joe Biden to visit Ireland or to visit the US at a later date.
He added that politicians "should not jump the queue" when it came to vaccinations.
Earlier this week, Chief Medical Officer Dr Tony Holohan said that he foresees another summer without non-essential foreign travel.
"I don't think we're headed for a summer where millions of people can be expecting to go to beaches other than in their own localities," he said.
"I don't think it's realistic to foresee a summer that would be characterised by things we would all like to do, where we would travel off to Europe for holidays," he said.
Dr Holohan emphasised that NPHET's advice is against all forms of non-essential travel for the foreseeable future.