There have been five additional deaths related to Covid-19 in Ireland, and a further 335 cases have been confirmed.
There has been a total of 1,945 Covid-19 related deaths in Ireland.
There are now 284 Covid-19 patients in hospital, 40 of whom are in Intensive Care Units, a rise of three from yesterday.
Of the cases notified today; 155 are men and 177 are women. 64% are under 45, and the median age is 37.
72 of today's cases are in Dublin, 41 in Donegal, 26 in Mayo, 25 in Cork, 23 in Kerry, and the remaining 148 cases are spread across 19 other counties.
Earlier, it was announced that there have been 15 further deaths related to Covid-19 and an additional 528 confirmed cases in Northern Ireland.
It brings the total number of coronavirus-related deaths in Northern Ireland to 774, according to figures from the Department of Health.
Twelve of the deaths occurred during the past 24 hours.
There are 391 confirmed Covid-19 inpatients in the hospital system, with 53 of those in intensive care.
There are now 22 beds available in ICU, and 101 beds in the wider hospital system, officials said.
Based on the relative population sizes, the 15 deaths which occurred are equivalent to around 38 deaths south of the border.
The 7-day infection rate per 100,000 for Northern Ireland is 212.9
The highest rate - 312.5 - is in the Mid Ulster Council area, followed by Lisburn and Castlereagh on 229.4.
The rate in Derry City and Strabane, once the area with the highest rate of infection anywhere on the island of Ireland or within the UK, is now 290.0.
The Northern Ireland Executive will meet tomorrow to discuss whether to extend current coronavirus restrictions, which are due to end on Friday.
Meanwhile, the Stormont Executive has imposed a 14-day isolation period for anyone arriving from Denmark because of concerns about a new strain of coronavirus that has spread from mink to humans.
Anyone who has arrived in Northern Ireland since 23 October, and all members of their household, must isolate for two weeks from the date they left Denmark.
The UK Government announced that from 4am this morning, all non-British national or resident travellers who have been in or transited through Denmark in the last 14 days will be denied entry into the UK.
There are no direct flights between Northern Ireland and Denmark, so any visitors would arrive via Britain or the Republic, as there are flights into Dublin.
There are no mink farms in Northern Ireland, but there are three in the Republic.
Northern Ireland's health minister Robin Swann has spoken to his counterpart Stephen Donnelly about the development.
Northern Ireland's chief medical officer Dr Michael McBride said: "Self-isolation for anyone who has been in Denmark is a mandatory requirement and it applies to all members of the household".
"This is an emerging picture and a precautionary approach is required at this early stage", he said, adding that "advice and guidance have been issued to health service colleagues in Northern Ireland".
Dr McBride added: "The UK authorities are working closely with international partners to understand the changes in the virus that have been reported in Denmark.
"A programme of further research in the UK will inform risk assessments."
Denmark's State Serum Institute, which deals with infectious diseases, has found mink-related versions of coronavirus in 214 people since June, according to a report on its website on Thursday.
One strain of the mutated coronavirus, which has prompted Denmark to cull its entire herd of mink, has however only been found in 12 people and on five mink farms so far.
While the mutated strain is not believed to be more dangerous, public health officials fear it could undermine the efficacy of a future vaccine.
The World Health Organization's lead for Covid-19, Maria van Kerkhove, said the WHO is looking at bio-security in countries where there are mink farms.
She said the transmission of the virus between animals and humans was "a concern". The risk was much lower in animals other than mink, she added.
"We are working with regional offices... where there are mink farms, and looking at biosecurity and to prevent spillover events,"
