The Neurology Support Centre [NSC] in Co Sligo which works with approximately 40 service users in the north west is set to wind-down after 13 years in operation.
In a statement, the board of the charity said it expects that the main operations will cease on 25 June. Plans are being put in place to provide support for exercise classes and peer support groups for up to 12 months, it added.
The centre, formerly the Northwest Neurological Institute works with individuals facing complex, long-term neurological condition.
It offers individuals support groups, counselling services, reflexology and exercise classes, and advocates on behalf of patients and provides transport for medical appointments.
The NSC board has written to service users, medical professionals and other stakeholders in the region to advise them of the winding down of operations.
The centre was founded in 2013 by the late Declan Walsh, following the diagnosis of his wife Natalie with Multiple Sclerosis and subsequently Progressive Multifocal Leukoencephalopathy.
Mr Walsh, together with Ms Walsh's father, Pat Murphy, successfully campaigned for funding to establish the centre as a recognised charity.
Chairman of the NSC Dr John Cannon said the board's decision was the most responsible course of action, given the circumstances.
Dr Cannon said they faced challenges for some time including some overlap in certain services provided by other charities in the region and a challenging fundraising situation.
"The charity was established originally on the basis of a substantial endowment for which we were very grateful, and while that endowment enabled us to do all the important work which we have done, it is depleted, and it has not been possible to secure the level of sustainable funding that would be necessary to continue our work into the future," he said.
Dr Cannon said they always managed the charity prudently and believe it was their responsibility to manage an orderly wind down rather than risk a more difficult set of decisions later in the year.
He paid tribute to the late Declan Walsh and his wife Natalie Murphy and said the work of the centre would not have been possible without their effort, vision and generosity.
Executive Director Bernadette Crilly said that although they were saddened to make the announcement, they are "incredibly proud" of the work done and the support provided to many people in the north west over the past 13 years.
"The resilience, dignity and appreciation of our service users have been inspiring and fueled our determination to do as much as we possibly could for people with neurological conditions," she said.
"I believe we have made a valuable contribution over that time and our focus in the coming months will be on supporting members and helping oversee transitional arrangements with other service providers in the region."
