Intellectual disability and mental health services provider, Nua Healthcare, is to create 470 jobs.
The company which provides residential, supported living, day and community outreach services to children and adults with a range of complex requirements, said the new roles come amid increased demand in the sector.
The jobs are in general nursing, psychiatric nursing, psychiatrists, psychologists, behavioural and occupational therapists.
The company is also recruiting assistant support workers and social care workers.
Nua Healthcare already employs more than 2,000 people across the country.
The company has taken on 300 people since the start of March.
"The healthcare industry is incredibly rewarding, and we take great pride in making a positive difference to the lives of the people we support" said Shane Kenny, Chief Operating Officer for Nua Healthcare.
"We also believe a core reason for success stems from the approach of continually training and developing staff teams," he continued.
"We are especially looking for people who may want to change their current career path and who believe they have compatible skills born out of relevant life experience which will ultimately enable them to be successful in healthcare services," he added.
Nua Healthcare is planning to open seven new facilities in counties Galway, Longford, Cavan, Cork, Carlow, Westmeath and Wicklow.
The new jobs will be based at their facilities nationwide.