Carmaker Nissan has scrapped plans to build its new X-Trail SUV in Britain and will produce it solely in Japan, warning two months before Brexit that uncertainty over Britain's departure was making it harder to plan for the future.
Falling demand for diesel cars in Europe has forced Nissan to invest in other technologies and save costs.
It cut hundreds of jobs at its Sunderland factory in the north of England, Britain's biggest car plant, last year as output slumped 11%, hit by levies and crackdowns on diesel.
"Nissan has increased its investments in new power trains and technology for its future European vehicles," the firm said.
"Therefore the company has decided to optimise its investments in Europe by consolidating X-Trail production in Kyushu."
"While we have taken this decision for business reasons, the continued uncertainty around the UK’s future relationship with the EU is not helping companies like ours to plan for the future," said Europe Chairman Gianluca de Ficchy.
Britain's business minister Greg Clark described the announcement as a "blow to the sector and the region."
Britain is due to leave the European Union on 29 March.
MPs last month rejected Prime Minister Theresa May's Brexit deal, heightening fears of a disorderly no-deal Brexit and of new trade barriers.
Mrs May has said she would seek a "pragmatic solution".
"We have a task force in place, reporting to me, that is considering all of the possible scenarios and the potential impact on the business," Mr de Ficchy said in a letter to workers.
Nissan builds roughly 30% of the country's 1.52 million cars and exports the vast majority to the continent.
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It said four months after Britain voted to leave the EU in June 2016 that it would manufacture the new X-Trail in Britain - a major vote of confidence in the country and Mrs May, shortly after she took office.
A source told Reuters at the time that Nissan received a letter from the government promising extra support in the event that Brexit hit the competitiveness of the Sunderland plant.
The new X-Trail could have created hundreds of jobs.
The carmaker's planned investment in the next-generation Juke and Qashqai models, which was also announced in 2016, was unaffected, the firm said.
The timing of the announcement comes just two days after an EU-Japan free trade agreement kicked in, which includes the European Union's commitment to removing tariffs of 10% on imported Japanese cars.
Many Japanese companies had long seen Britain as the gateway into Europe, after being encouraged to open factories in the country by former prime minister Margaret Thatcher but Brexit has thrown that into doubt, prompting consternation in Tokyo.
The announcement also comes as the firm continues to deal with the fallout from the arrest of its former boss Carlos Ghosn, which has clouded the outlook for the automaking alliance between Nissan, Renault and Mitsubishi.
