Taoiseach Enda Kenny met with the leaders of the Netherlands and Denmark in The Hague today as the three countries seek to minimise the impact of Britain's divorce from the EU.
"Given the extent of trade between our three countries and the United Kingdom, it's very important that there will be clarity and movement to those issues as soon as it's appropriate," said Mr Kenny.
"We want to minimise any major impact to our economy as with the Netherlands and Denmark," he added.
Like Ireland, Denmark and The Netherlands are heavily dependent on trade with Britain.
Mr Kenny, who recently met the Spanish, Polish, Belgian and German leaders, said: "We want to protect jobs, we want to grow jobs and increase prosperity.
"We want to provide as much clarity and certainty for businesses from our three countries about trade with United Kingdom," he added.
But Mr Kenny highlighted: "The agenda of the European Union is beyond Brexit ... with opportunities for expansion, job creation, investment and above all continued peace, and that should not be derailed by the Brexit negotiations."
Dutch Prime Minister Mark Rutte said the EU needed to "act in concert" during the Brexit negotiations, saying "unity" was in everyone's best interests.
"We will need to have, as 27 countries, a unified position with one negotiator working on behalf of all of us," he said, after the talks with Mr Kenny and his Danish counterpart Lars Lokke Rasmussen.
The remaining 27 EU countries are set to rubber-stamp negotiating guidelines from the EU President Donald Tusk at a European Council summit on 29 April.
"Our countries are potentially among the countries which will be most affected by the Brexit," Mr Rasmussen told a joint press conference.
"We need to reduce the damages of Brexit as much as possible and build a new working relationship."
A Dutch government think-tank warned last year before Britain's referendum that Brexit could cost The Netherlands a 1.2% fall in GDP by 2030 and a €10bn trade loss.
Mr Rutte stressed that some of the burning issues were the status of EU citizens living in Britain, as well as European business located there, Britain's potential Brexit "bill" and the issue of borders.