Kamala Harris has accepted the Democratic presidential nomination in Chicago before a rapturous crowd, pledging a "new way forward" if she beats Republican Donald Trump in November's election.
The 59-year-old sought to strike a presidential tone as she delivered a message of unity and opportunity for Americans following one of the most extraordinary turnarounds in US political history.
She lashed out at Mr Trump, accusing him of trying to "take our country" backwards and of cosying up to foreign "tyrants" like Russian President Vladimir Putin.
Ms Harris made a rousing call to end the war in Gaza and to fight tyranny around the world, drawing a sharp contrast with Mr Trump.
"In the enduring struggle between democracy and tyranny, I know where I stand and I know where the United States belongs," Ms Harris said, accusing Mr Trump of bowing down to dictators.
Ms Harris emerged as the Democratic candidate little more than a month ago when allies of President Joe Biden, 81, forced him to quit the race.
It was a forceful speech for a candidate who, during her brief campaign, had yet to articulate much of her vision for the country and faced a stream of personal attacks from Mr Trump, who mocked her black and South Asian heritage and called her weak on the foreign stage.
The speech laid out some broad policy principles, foreign and domestic, but left unsaid specific details which in weeks to come she could be pressured to provide.
After days of protests from Palestinian supporters who were disappointed at not getting a speaking spot at the convention, Ms Harris delivered a pledge to secure Israel, bring the hostages home from Gaza and end the war in the Palestinian enclave.
"Now is the time to get a hostage deal and a ceasefire deal done," she said to cheers.
"And let me be clear, I will always stand up for Israel's right to defend itself and I will always ensure Israel has the ability to defend itself."
"What has happened in Gaza over the past 10 months is devastating. So many innocent lives lost, desperate hungry people fleeing for safety over and over again. The scale of suffering is heartbreaking," she said.
"President Biden and I are working to end this war such that Israel is secure, the hostages are released, the suffering in Gaza ends and the Palestinian people can realise their right to dignity, security, freedom and self-determination."
In some of her strongest foreign policy statements to date, Ms Harris said she would take whatever action was necessary to defend US interests against Iran and would not cosy up to tyrants and dictators.
She said such leaders, including North Korea's Kim Jong-un, "are rooting for Trump."
She vowed to stand with Ukraine in its war against Russia and with NATO allies.
If successful, Ms Harris stands to make history as the first woman elected US president.
She described the 5 November election as a "precious, fleeting opportunity to move past the bitterness, cynicism and divisive battles of the past. A chance to chart a new way forward."
Ms Harris drew a series of contrasts with Mr Trump, accusing him of not fighting for the middle class, planning to enact a tax hike through his tariff proposals, and having set in motion the end of a constitutional right to abortion with his picks for the US Supreme Court.
She noted the Supreme Court's recent ruling about presidential immunity and the risks that would engender if Mr Trump gained power again.
"Just imagine Donald Trump with no guard rails," she said.
Mr Trump, who had promised to respond to Ms Harris's speech in real time, posted a series of messages on Truth Social as she spoke about him, including: "She stands for Incompetence and Weakness - Our Country is being laughed at all over the World!" and "She will never be respected by the Tyrants of the World!"
Chicago's United Centre brimmed with energy - and people.
The arena’s 23,500 seats were filled and arena staff briefly blocked more people from entering the facility, saying the city’s fire marshal declared the building at capacity.
After Ms Harris ended her speech, 100,000 balloons descended on the crowd, a convention official said. Inflating them took 75 volunteers, 30 staff members and a dozen unionised stagehands.
Mr Biden called Ms Harris to wish her luck before her speech, a White House spokesperson said.
Last night, Ms Harris said she will pass a middle tax cut that will benefit more than 100 million Americans.
She discussed her plans to fight for abortion rights, voting rights legislation, boost the housing supply and ban what she has called "price gouging" by grocers.
Her campaign has also proposed raising the corporate tax rate from 21% to 28%.
Read more:
5 takeaways from the Democratic National Convention
Before the speech, thousands of Palestinian supporters once again gathered to protest US support for Israel as it wages war in Gaza.
The issue is one of the most divisive among Democrats and got little attention at the convention, which could hurt Democrats at the polls.
Delegates from the Uncommitted National Movement, which mobilised nearly 750,000 voters to withhold support for Mr Biden during the presidential primaries, entered the venue linking arms and took their seats.
Members spent Wednesday night on the footpath outside the convention to protest the DNC's rejection of their request for a Palestinian speaker.
Ms Harris has raised a record-breaking $500 million in a month and narrowed the gap or taken the lead against Mr Trump in many opinion polls of battleground states.
Nationwide, she leads Mr Trump 46.6% to 43.8%, according to a compilation of polls by FiveThirtyEight.
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