The White House has said that US intelligence based on aerial images and intercepted communications shows Israel was not to blame for this week's strike on a Gaza hospital that killed hundreds.
"While we continue to collect information, our current assessment, based on analysis of overhead imagery, intercepts and open source information, is that Israel is not responsible for the explosion at the hospital in Gaza yesterday," National Security Council spokeswoman Adrienne Watson said on social media.
The comments came after US President Joe Biden - who has since left Tel Aviv on what became the only stop on his visit to the Middle East - earlier told reporters that "based on the information we've seen to date" the strike on the hospital "appears as a result of an errant rocket fired by a terrorist group in Gaza".
He said the assessment relied on "data I was shown by my defence department".
Palestinian officials blamed an Israeli air strike for the fireball that engulfed the Al-Ahli al-Arabi hospital yesterday evening, which they said had killed 471 people.
Israel said the blast was caused by a failed rocket launch by the Palestinian Islamic Jihad militant group, which denied blame.
Arab leaders responded to the loss of life, which they blamed on Israel, by cancelling a summit with Mr Biden in Jordan. This had been intended as the second half of his carefully choreographed itinerary for emergency meetings with allies to avert a wider war in the region.
Speaking alongside Israeli Prime Minister Benjamin Netanyahu, Mr Biden said: "I was deeply saddened and outraged by the explosion of the hospital in Gaza yesterday, and based on what I've seen, it appears as though it was done by the other team, not you."
"But there's a lot of people out there not sure, so we've got a lot, we've got to overcome a lot of things," Mr Biden added.
The US President’s trip to the Middle East was designed to calm the region, even as he demonstrated US support for its ally Israel, which has vowed to annihilate the Hamas movement whose fighters killed 1,400 Israelis in a rampage on 7 October.
But after the hospital blast, Jordan cancelled the planned Amman summit where Mr Biden had been due to meet the leaders of Jordan, Egypt and the Palestinian Authority. Instead, he was expected to speak to the Jordanian and Egyptian leaders by phone from Air Force One on the way home.
Israeli President Isaac Herzog's office said he had told Mr Biden: "God bless you for protecting the nation of Israel."
Mr Netanyahu thanked Mr Biden for his "unequivocal support".
After his talks with Mr Netanyahu’s war cabinet, Mr Biden held an emotional meeting with Israeli survivors of the 7 October attack.
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The accounts of destruction at the hospital were horrific even by the standards of the past 12 days, which have confronted the world with relentless images, first of Israelis killed in their homes and then of Palestinian families buried under rubble from Israel's retaliatory strikes.
Rescue workers scoured blood-stained debris for survivors. A Gaza civil defence chief gave a death toll of 300, while the health ministry put it at 471, though Israel disputed those figures. Palestinian ministry spokesperson Ashraf Al-Qudra said rescuers were still recovering bodies.
"People came running into the surgery department screaming, 'Help us, help us, there are people killed and wounded inside the hospital!'" said Dr Fadel Naim, head of the hospital's Orthopedic Surgery Department.
"The hospital was full of dead and wounded, dismembered bodies," he told Reuters. "We tried to save whoever could be saved but the number was too big for the hospital team..."
Israel later released drone footage of the scene of the explosion, which it said showed it was not responsible because there was no impact crater from any missile or bomb and no structural damage to surrounding buildings.
The Israeli military published what it said was an audio recording of "communication between terrorists talking about rockets misfiring".
Palestinians were convinced the explosion was an Israeli attack, with no warning for civilians to leave a hospital being used as a shelter by Gazans already made homeless by bombing.
"This place created a safe haven for women and children, those who escaped the Israeli bombing," another doctor at the hospital, Ibrahim Al-Naqa, told Reuters. "We don't know what the shell is called, but we saw the results of it when it targeted children and ripped their bodies into pieces."
A third doctor, British-Palestinian Ghassan Abusittah, said the hospital had shaken all day because of bombing. He heard the sound of a missile just before a huge explosion and then the operating room ceiling collapsed. In the courtyard he said he could see bodies and limbs everywhere. Dr Abusittah said he then treated a man whose legs were blown off.
World leaders from UN Secretary General Antonio Guterres to Russian President Vladimir Putin denounced the blast in statements that nonetheless avoided addressing who was to blame.
Britain's Foreign Secretary James Cleverly said too many people had "jumped to conclusions" about the cause of the blast.
"Getting this wrong would put even more lives at risk. Wait for the facts, report them clearly and accurately. Cool heads must prevail," he posted on social media.
The blast unleashed fury across the Middle East.
Palestinian security forces fired tear gas and stun grenades to disperse anti-government protesters in the West Bank city of Ramallah, seat of Palestinian Authority President Mahmoud Abbas, one of the Arab leaders who cancelled a meeting with Biden.
Tensions also ran very high on Israel's border with Lebanon, where clashes between the Iran-backed Hezbollah movement and Israel over the past week have been the deadliest since the last all-out war in 2006.
Mr Biden was under intense pressure to win a clear Israeli commitment to let aid into Gaza from Egypt, to ease the plight of civilians in the besieged enclave.
As he wrapped up his visit, Mr Netanyahu's office put out a statement saying Israel would let food, water and medicines reach southern Gaza via Egypt. It reiterated that it would not let aid in from Israel until Hamas released its hostages.
