The Tánaiste has said that it will be August at the earliest when non-essential overseas travel will resume.
However, he said it was still too early to give further clarity as there are many uncertainties.
During a virtual press conference this morning, Leo Varadkar told journalists that he expects the EU Digital Green Certificate to be in place by mid-June, with member states then having six weeks to adopt it.
Mr Varadkar also said that some form of Mandatory Hotel Quarantine will likely remain in place for "quite some time".
He said he hopes that the Common Travel Area between Ireland and the UK will be restored "very soon", allowing people to travel to Britain without restrictions.
He said that he hopes it would happen at some point this summer or autumn.
Mr Varadkar said that he would like to see an arrangement with the United States, similar to an EU Digital Green Certificate system, to reopen travel at some point.
However, he warned that there will be large parts of the world that will not be fully vaccinated until the middle of next year.
He predicted that countries that pursued an elimination approach, such as New Zealand and Australia, will not be vaccinated for "a very long time as well".
Therefore, he said that hotel quarantine, for those travelling from high-risk areas, would likely have to remain in place.
For those travelling from the likes of the EU, Britain, US, and Israel, it might be possible to resume non-essential travel sooner, given their advanced vaccination programmes.