Russian opposition leader Alexei Navalny, who the West says was poisoned with a Novichok nerve agent, is regaining mobility and able to leave his bed, the Berlin hospital treating him said.
The improvement in Mr Navalny's condition came as two European laboratories corroborated the findings that the Soviet-era military grade agent was used on the Kremlin critic.
It prompted French President Emmanuel Macron to demand his Russian counterpart Vladimir Putin shed light on the "attempted murder".
Hitting back at doubts raised by Russia about the German investigation, Chancellor Angela Merkel's spokesman Steffen Seibert said Berlin had asked France and Sweden "for an independent review of the German evidence on the basis of new samples from Mr Navalny".
"The results of this review at specialised laboratories in France and Sweden are now available and confirm the German evidence" of the use of the banned weapons-grade substance, Mr Seibert said in a statement.
The results prompted Mr Macron to tell the Russian president in telephone talks that it was "imperative that all light be shed, without delay, on the circumstances of this attempted murder and who is responsible", the French presidency said in a statement.
Mr Putin fired back that the claims remained "unsubstantiated accusations based on nothing against the Russian side".
Although Germany was still waiting for the outcome of a separate evaluation by the OPCW global chemical weapons watchdog, Mr Seibert said Germany was renewing its call for Russia to make a "declaration on the events".
"We are in close contact with our European partners about further steps," he added.
Asa Scott, head of division for CBRN defence and security at Sweden's Defence Research Agency, confirmed its lab in Umea in the north of the country had found Novichok in the sample and presumed it came from Russia.
"I find it unlikely that any other nation that is party to the Chemical Weapons Convention would have it," Asa Scott said.
As the pressure on Moscow built, the German hospital treating Mr Navalny said his condition continued to improve.
"The patient has been successfully removed from mechanical ventilation," Berlin's Charite hospital said.
"He is currently undergoing mobilisation and is able to leave his bed for short periods of time."
The 44-year-old anti-corruption campaigner became ill in Siberia last month and was hospitalised there before being flown to Berlin.
Germany said there was "unequivocal evidence" he was poisoned with Novichok but Russia angrily dismissed the findings, saying its doctors found no trace of poison.
Western politicians have insisted the incident appears likely to have been state-ordered. The Kremlin has denounced attempts to blame the Russian state as "absurd".
Despite international calls for Russia to carry out a transparent investigation or risk sanctions, it has not opened a criminal probe.