The number of people who have died in hospitals in the UK after testing positive for the coronavirus has risen to 18,100, the health ministry said, marking an increase of 763 on the figures published 24 hours earlier.
The 763 increase is down from 828 in the previous period.
The number of confirmed cases of Covid-19 had risen to 133,495, it added.
The figure for deaths is as of 5pm on 21 April, while the figure for confirmed cases is as of 9am today.
Meanwhile, the death toll of people dying after contracting coronavirus in Northern Ireland has risen to 250.
Northern Ireland's Department of Health has said that eight deaths occurred in hospital yesterday and that a further 26 deaths that have been previously unreported have been added to official record.
In total 2,874 people in Northern Ireland have tested positive for the virus.
The figures were announced as the British government came under sustained pressure over all aspects of its coronavirus response as MPs got their first major opportunity in a month to hold it to account.
Dominic Raab, who is deputising for Prime Minister Boris Johnson, faced a barrage of tough questions during Prime Minister's Questions.
Mr Johnson is still recovering from Covid-19.
"Something's going wrong," Labour leader Keir Starmer said.
"And there's a pattern emerging here. We were slow into lockdown, slow on testing, slow on protective equipment, and are slow to take up these offers (to supply equipment) from British firms," he said.
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Mr Johnson initially stopped short of imposing stringent controls seen elsewhere in Europe as the coronavirus spread, but he later closed down the country when projections showed a quarter of a million people could die in the United Kingdom.
He faced a call for an independent inquiry into his and the government's handling of the outbreak after ministers struggled to explain shocking death rates, limited testing and reported shortages of protective kit in the places where they are most needed.
"Will the government commit itself now, for the future, to an independent judge-led inquiry into how this crisis has been handled?" said Liberal Democrats leader Ed Davey.
Mr Raab rejected his call.
"I have to say I won't take up his offer of committing to a public inquiry. I think that there are definitely lessons to be learned and when we get through this crisis it will be important that we take stock," he said.
In a novel, hybrid approach that broke with 700 years of parliamentary protocol, some members of parliament were present in the chamber, at safe distances from one another, while others participated via video link.
On the issue of reported shortages of protective equipment, Mr Raab made a limited concession that more needed to be done.
"We've delivered 1 billion items of personal protective equipment and tens of millions have been distributed via the devolved administrations (of Scotland, Wales and Northern Ireland)," he said.
"We recognise though that we have got to strive even harder in this incredibly difficult and competitive international environment to source the equipment."
Mr Raab also said the government was confident it would meet its target of carrying out 100,000 tests a day for the coronavirus by the end of the month.
Current capacity stands at 40,000 a day, he said, but the actual number of tests carriedout daily has hovered around the 20,000 mark.
England's chief medical officer said it was unrealistic to expect a sudden lifting of all lockdown restrictions, even as ministers say the UK has reached the peak of the coronavirus outbreak.
"If people are hoping that it's suddenly going to move from where we are now, in lockdown, suddenly into 'everything's gone', that is a wholly unrealistic expectation," Professor Chris Whitty told reporters.
"We're going to have to do a lot of things for really quite a long period of time."
Meanwhile, the number of coronavirus-related deaths in care homes in England and Wales between 11 and 15 April could be double that of the 1,043 deaths involving Covid-19 registered up to 10 April.
The warning came from the Department of Health and Care Quality Commission (CQC) who are working with the UK Office for National Statistics (ONS) to provide "a more detailed and timely picture of the impact of Covid-19 on adult social care".
The ONS said yesterday that there were 1,662 deaths involving Covid-19 in England and Wales registered up to 10 April which occurred outside hospitals. Of these, 1,043 took place in care homes.
In a statement, the CQC and department said: "The ONS data published yesterday covers the period until April 10.
"CQC's current preliminary analysis is up to April 15; it is anticipated that the number of deaths in care homes relating to Covid-19 reported by providers between April 11 and April 15 could be double the number of care home deaths reported yesterday.
"In common with the ONS, CQC's preliminary analysis also indicates there may be a significant rise in non-Covid-19 deaths. This is of particular concern."
