Three more people with Covid-19 have died in the Republic of Ireland, the National Public Health Emergency Team has said.

Two were female patients in the east, with the other person in the northwest.

Tonight, Taoiseach Leo Varadkar expressed his condolences to the families and friends of those who died today, one of whom was a healthcare worker.

There have now been 22 coronavirus-related deaths in the country.

The Health Protection Surveillance Centre (HPSC) has also been informed of 302 new confirmed cases of Covid-19. That brings to 2,121 the number of confirmed cases here.

The HSE is now working to identify any contacts the patients may have had to provide them with information and advice to prevent further spread.

The latest data from the HPSC, based on data as of midnight, Wednesday 25 March, shows that 54% of cases are male and 46% are female, with 79 clusters involving 317 cases

The median age of confirmed cases is 46 years of age.

Over 419 cases (26%) have been hospitalised. Of those, 59 cases have been admitted to ICU.

So far, 375 cases (23%) are associated with healthcare workers.

Dublin has the highest number of cases at 922 - 56% of all cases - followed by Cork with 171 cases (10%).

Of those for whom transmission status is known; community transmission accounts for 52%, close contact accounts for 22% and travel abroad accounts for 26%.

Around 80% of cases of Covid-19 will be a mild to moderate illness, close to 14% of patients have severe disease and around 6% are critical.

Generally, you need to be 15 minutes or more in the vicinity of an infected person, within 1 to 2 metres, to be considered at risk or a close contact.