The Association of Secondary Teachers Ireland has decided to hold seven days of strike action between now and December.
Members will strike on 27 October, 8 November, 16 November, 24 November, 29 November, 6 December and 7 December.
They will also withdraw from supervision and substitution duties from 7 November.
Secondary schools across the country will close on the announced dates in the dispute over pay for newly-qualified teachers as well as payment for supervision and substitution duties.
Commenting on the unequal pay arrangements, ASTI President Ed Byrne said: "The sense of injustice amongst all teachers is palpable. ASTI members are committed to achieving equal pay for equal work for all teachers."
"Teachers are reluctant to take industrial action or to interrupt the running of schools in anyway. However, we have flagged our serious issues well in advance and remain available and committed to a resolution through talks without pre-conditions," added Mr Byrne.
The ASTI is Ireland's largest second-level teachers' union with 17,500 members teaching in more than 520 schools nationwide.
A spokesperson for Minister for Education Richard Bruton said he noted the decision with disappointment.
In a statement, the Department of Education said: "ASTI's decision means that severe disruption to students and parents is inevitable, with widespread school closures anticipated with effect from 27 October.
"Prior to this decision, the department had requested that ASTI would cooperate with contingency plans designed to keep schools open in the event of their members withdrawing from S&S duties. In particular, the Department requested that ASTI would give sufficient notice of members' withdrawal from S&S duties to allow time for external personnel to be recruited, trained and undergo Garda vetting etc.
"It is regrettable that ASTI have decided not to cooperate with the contingency arrangements.
"Despite ASTI's decision, the department and school management bodies will proceed to finalise contingency arrangements."
The Director of the National Association of Principals and Deputy Principals has called on all sides to the dispute to engage in negotiations as soon as possible.
Speaking in Galway, Clive Byrne said this evening's announcement by the ASTI was not unexpected but the timeframe for industrial action had taken people by surprise.
He said the decision to strike before the mid-term break would complicate efforts to resolve differences between the union and the Department of Education.
This will also hamper department efforts to have people in place with garda vetting, to carry out supervision and substitution duties.
Mr Byrne said the NAPD hoped a resolution that meets the needs of students, parents and teachers could be found.
While the association has no role in discussions, it wants to see talks beginning as soon as possible.
Mr Byrne reiterated concerns expressed during the two day NAPD conference in Galway about the impact strike action could have on staff morale and trust levels in secondary schools.
