A fresh appeal has been issued to help find Dublin woman Karen Scott who has been missing since last Friday.
Inspector John Burke of Finglas Garda station said their greater concern is her vulnerability as Ms Scott has Down syndrome.
Gardaí say the last sighting was CCTV footage of Ms Scott leaving a pub on Burgh Quay, Dublin 2 at 9.40pm on 24 June.
She left and turned onto D'Olier St. Other CCTV footage showed Ms Scott on Berkeley Road in Phibsborough on the same day.
When last seen Ms Scott was wearing a peach coloured hooded top, black jeans and white runners. She is 1.62m (5'4") tall of medium build with blue eyes and short blonde hair.
She also had a red suitcase with her, which had other clothes in it, including brightly coloured green, yellow and blue tops as well as a mini skirt and shorts.
Gardaí do not believe that Ms Scott was going to meet anyone but are anxious to talk to anyone who may have met her since Friday evening.
They also believe she may have had some money, but does not have a phone with her.
It is also believed Ms Scott is not carrying a passport or bus pass.
Inspector Burke said: "We are working closely with Karen's family to try and locate her. We would appeal to anybody who has any information, however small, to contact us.
"Due to Karen being missing for a number of days, we and Karen's family, are very concerned for her safety".
Anyone with information is asked to contact Finglas Garda station 01 666 7500, the Garda Confidential Line on 1800 666 111 or any garda station.