The United States warned its citizens about "credible threats" to tourist areas in Turkey, particularly in Istanbul and the southwest coastal resort of Antalya.
Turkey has been hit by four suicide bombings already this year, the most recent one last month in Istanbul.
Two of those have been blamed on the so-called Islamic State, while Kurdish militants have claimed responsibility for the other two.
In what it called an "emergency message", the US Embassy in Turkey warned US citizens to exercise extreme caution.
"The US Mission in Turkey would like to inform US citizens that there are credible threats to tourist areas, in particular to public squares and docks in Istanbul and Antalya," it said the statement emailed to US citizens in Turkey.
Last month's attack in Istanbul's main shopping district killed three Israelis, two of whom held dual citizenship with the United States, and one Iranian.
A number of Irish people were also caught up in the attack.
A separate attack in the city's historic heart in January killed 12 German tourists.
Turkey is facing multiple security threats.
As part of a US-led coalition, it is fighting IS in neighbouring Syria and Iraq.
It is also battling Kurdish militants in its southeast, where a two-and-a-half ceasefire collapsed last July, triggering the worst violence since the 1990s.
Three people were wounded when a bomb exploded near a bus stop in Istanbul today, the Dogan news agency reported.
The blast went off in the busy district of Mecidiyekoy in the European side of the city.
The three wounded were hospitalised but were only lightly injured, the report said.