The LÉ Samuel Beckett has docked in Cork Harbour following a three-month tour of duty in the Mediterranean.
The naval vessel carried out humanitarian and search and rescue operations in the region during the tour.
The crew rescued more than 1,000 migrants during five of its operations, carried out with the Italian Maritime Rescue Coordination Centre.
The crew of 58 sailors on board was accompanied by medics from the Army and the Air Corps.
Led by Lieutenant Commander Anthony Geraghty, they will be met by the Flag Officer Commanding the Naval Service, Commodore Hugh Tully, when they dock at the Naval Base in Haulbowline.
The Captain of the LÉ Samuel Beckett has said there are still people attempting to cross the Mediterranean, but he said the numbers have decreased slightly.
Speaking on RTÉ's Morning Ireland, Lt Cdr Geraghty said the pace of their operation did slow towards the end of their deployment, as was expected during the winter months.
He said the crew worked closely with the Italian coastguard, as well as carrying out their own searches of risk-assessed waters.