The United States has condemned a series of stabbings in Tel Aviv and the West Bank, urging both Israelis and Palestinians to ease rising tensions.
An Israeli woman was killed and two others wounded today, in an attack outside a West Bank settlement.
Elsewhere, an Israeli soldier also died after being attacked with a knife in Tel Aviv by a Palestinian teenager.
The soldier's stabbing brought bloodshed to the Israeli commercial capital that has largely been spared since the previous uprising died down in 2005.
Police identified the suspected assailant, who was arrested, as a resident of the occupied West Bank who was in Israel illegally and had not previously been arrested.
Hours later, a Palestinian stormed out of a car to stab three people outside the Jewish settlement of Alon Shvut in the West Bank, killing the woman and wounded two other people, police said.
The attacker was shot and wounded by a guard.
The militant group Islamic Jihad claimed him as its member and an Israeli security official said he had been jailed in Israel between 2000 and 2005 for a petrol bomb attack.
Israeli-Palestinian bloodshed has risen over Israeli-controlled access to Jerusalem's Al-Aqsa mosque compound, Islam's third holiest site, where biblical Jewish temples once stood.
Stone-throwing protests have erupted in several Arab towns in Israel since Saturday, when police killed an Arab youth who assaulted them.
Last week a Palestinian rammed his car into pedestrians in central Jerusalem, the second such incident in as many weeks, killing two Israelis.
Police shot the driver dead.
"We strongly condemn the stabbing today in the West Bank, and we deeply regret the loss of life," State Department spokeswoman Jen Psaki said.
"Our condolences go out to the victim's family. It is absolutely critical that parties take every possible measure to protect civilians and de-escalate tensions."
Washington was also seeking further information from the Israeli justice ministry on Saturday's shooting of an Israeli-Arab in Galilee.
"There have been a range of issues and events that have led to the rising tensions in the region, that both sides need to do more to fix," Ms Psaki told reporters.
