Iran's Supreme Leader Ayatollah Ali Khamenei has said his country needs to significantly increase its number of centrifuges.
His comments underline a gap in positions between Tehran and world powers as they hold talks aimed at securing a nuclear accord.
They have less than two weeks to reach an agreement on the future of Iran's uranium enrichment programme and other issues if they are to meet a self-imposed 20 July deadline for a deal.
Iran's enrichment capacity lies at the centre of the nuclear stalemate and is seen as the hardest issue to resolve.
Iran insists it needs to expand its capacity to refine uranium to fuel a planned network of atomic energy plants.
The powers say Tehran must sharply reduce the capacity to prevent it being able to quickly produce a nuclear bomb.
"Their aim is that we accept a capacity of 10,000 separative work units (SWUs), which is equivalent to 10,000 centrifuges of the older type that we already have.
"Our officials say we need 190,000 centrifuges. Perhaps this is not a need this year or in two years or five years, but this is the country's absolute need," Mr Khamenei said in a statement published on his website.
"The P5+1 started bargaining with 500 SWUs, then 1,000 SWUs enrichment capacity. Now they want to convince us to (accept) 10,000 SWUs," he added.
Tehran says its programme is solely for civilian purposes such as electricity generation and denies any plan to build an atomic bomb.
Iran now has more than 19,000 installed enrichment centrifuges, mostly old-generation IR-1 machines, with about 10,000 of them operating to increase the concentration of uranium's fissile isotope U-235.
In 2006, when the UN Security Council imposed its first sanctions resolution against the country, Iran had a few hundred centrifuges that it was testing.
Iran has since expanded the number sharply until it stopped doing that under the 24 November interim nuclear deal agreed between Iran and the world powers.