Four companies are to create 150 jobs in Dublin.
Two Indian companies are establishing offices in the capital, creating 75 jobs between them.
Aditi Technologies is setting up a European Services and Business Development Centre with the creation of 40 jobs.
Synowledge has announced 35 positions as it establishes an international headquarters in Dublin.
Meanwhile, 50 jobs are to be provided in Dublin over the next 18 months by loyalty card company Value Nation.
Online publishing company Maximum Media today announced the creation of 25 jobs in Dublin over the next 12 months.
Ten of the new jobs come into effect immediately.
Minister for Jobs, Enterprise and Innovation Richard Bruton said the job announcements by Aditi and Synowledge show that Ireland is a good gateway to Europe.