All patients with emergency cardiology or medical problems will no longer be treated at Nenagh General Hospital from 17 September.
The Health Service Executive said these patients will instead be assessed and treated at the Emergency Department at the Mid-Western Regional Hospital in Limerick.
From 17 September a local injuries unit in Nenagh General will be open from 8am to 8pm to deal with minor cases and all emergency will go straight to Limerick.
Nenagh General lost its 24-hour Emergency Department in April 2009, when it was changed to a 12-hour Local Emergency Centre.
The HSE Mid-West said the change is in line with the National Emergency Medicine Programme and will allow the centralisation of emergency care for the sickest patients in the region to Limerick.
Nenagh hospital will continue to admit GP-referred medical patients with an accompanying letter, with less critical conditions for assessment and treatment in the Medical Assessment Unit.
The existing Local Emergency Centre has been treating 8,000 cases a year.
The HSE said the local injuries unit to replace it will deal with adults and children over five years and cases such as broken bones, soft tissue injuries and wounds.
The HSE said all staff, patient groups, GPs and public representatives are being briefed on the development.
