Those campaigning for a No vote in the fiscal treaty have accused the Taoiseach of scaremongering after Enda Kenny said rejection of the treaty would lead to uncertainty and confusion.
Meanwhile, the group set-up to oppose household and water charges formally declared that they would also be campaigning for a No vote.
While canvassing for a Yes vote in the referendum in Limerick today, Mr Kenny said a Yes vote was a yes to the euro, to Europe and the European Union.
He said a No vote was for uncertainty, for confusion, for lack of confidence and a lack of belief in ourselves, and he was completely opposed to that.
He said people continued to ask questions about the treaty and rightly so, but he was impressed that they were informing themselves about the issues.
However, Sinn Féin TD Mary Lou McDonald has said the Government's contribution to the debate on the fiscal treaty has been nothing short of a disgrace.
Speaking after she attended an Irish Feminist Network Conference, she said with just two weeks remaining the Government needs to debate causes and consequences of the treaty.
She said Mr Kenny would prefer make far-fetched comments about Ireland's future rather than debate the treaty.
She again called on the Taoiseach to debate one-to-one with Gerry Adams.
Socialist Party TD Joe Higgins has also accused the Taoiseach of trying to blackmail the electorate into voting yes.
Mr Higgins said the Taoiseach's comments that a Yes vote would mean yes to the euro and to Europe is absolutely false.
He said a no vote would send a signal of solidarity with other Europeans who are currently revolting against the policy of austerity.
Elsewhere, Tánaiste Eamon Gilmore said the Irish people have an opportunity on 31 May to make a positive statement that the people want a stable euro, investor confidence and want access to emergency funding if needed.
Speaking as he campaigned in Dún Laoghaire, Mr Gilmore welcomed US President Barack Obama's comments yesterday about the necessity for a growth agenda in Europe.
Referring to next week's European summit, Mr Gilmore said the Government would be arguing for growth, for measures relating to wider use of the European Investment Fund and for better use of unused Structural Funds to stimulate growth.
He dismissed Mary Lou McDonald's comments as "catcalling" and said the Government is focusing on the positives of the treaty.