Taoiseach Enda Kenny has said a Yes vote in the forthcoming referendum on the Fiscal Treaty will be crucial for Ireland's economic future.
Speaking on RTÉ's The Week in Politics, Mr Kenny urged voters not to reject the Treaty.
He said it would be a ''one shot referendum because this has to be approved by 1 January next year.''
"Whatever differences we have at home, whatever differences we are having among ourselves I would say to the Irish people - do not kick the future in the face."
"The train leaves on 1 January next and we want to be on that."
Mr Kenny was asked about recent events where Denis O'Brien was in attendance.
Speaking about Mr O'Brien's attendance at meetings of the Global Economic Forum, the Taoiseach said all those who attended the first meeting were invited to the second.
He said the Tánaiste was working on the follow through to the last meeting and added - "the Government will reflect on what it does for any future forums."
In relation to his visit to the New York Stock Exchange and Mr O'Brien's presence at that event, the Taoiseach said he did not issue the invitations.
He said: "Was I supposed to stay outside the door and say, Sorry I can't go on this platform."
And he added: "Or if I find myself at a Connacht final and find myself two seats away from former Minister Flynn, what I am to do, get up and walk out?" ÁÍÓÚÉ áíóúé
"I accept invitations as Taoiseach to attend particular functions. I do not vet, and cannot and won't be in a position to vet the lists of those who attend."
The Taoiseach said he accepted the Government has a responsibility in what it does in its actions with people.
He repeated the Government had forwarded the reports of the Moriarty and Mahon tribunals to all the relevant agencies to discharge their independent roles.
Earlier, Deputy Leader of Fine Gael James Reilly said that Mr O'Brien is entitled to due process.
He was commenting on This Week on the controversy over Mr O'Brien appearing at official functions, despite certain adverse findings in the Moriarty Report.
Dr Reilly also said he accepted the findings of the Moriarty Tribunal.
The Minister for Health said he agreed that the Cabinet should decide who would be invited to the next Global Economic Forum.
However, he added that Government had made no decisions on the matter yet.
