Minister for Education Ruairi Quinn has announced details of 219 new school building projects.
The new schools will be built over the next five years as part of a €1.5bn programme.
The new projects are in addition to 56 school building projects already announced for 2012.
Mr Quinn said this investment will create an estimated 15,000 direct and 3,000 indirect jobs over the period of the programme.
The plan sees the construction of 106 primary schools, 43 secondary schools and eight special schools.
There will be extensions to 65 primary schools, 49 secondary schools and four special schools.
The Government said the plan is necessary to meet the demands placed on the education system by the baby boom of the last decade.
Mr Quinn said: "We have to ensure that every child growing up in Ireland can access a physical school place.
"Our programme … means that schools and parents will be able to plan much better for their children's education at a time when enrolments at both primary and second level are rising dramatically."
The Irish National Teachers' Organisation has disputed the claim that 106 primary schools will be built.
INTO General Secretary Sheila Nunan said: "Today's announcement is good news for the schools concerned, although many will still have to endure unsatisfactory buildings for several more years.
"There are many more schools in need of urgent upgrade which are not covered in this announcement. Parents and teachers will want to know when those school buildings will be addressed."