6,350 redundancies were notified to the Department of Enterprise, Trade & Employment in July, an increase of almost 65% compared with the same month last year.
The percentage rise compares with increases of more than 200% in some of the earlier months of the year.
For the first seven months of the year, lay-offs are up 142%, from 20,255 to 49,009. This is almost 10,000 more redundancies than in the whole of 2008.
Live Register figures for July will be released later this week.
Small business group ISME described the figures as 'dismal', and called on the Government to set up a National Employment Task Force to stop the haemorrhaging of jobs.
Director of the Small Firms Association Patricia Callan urged the Government to take 'decisive action' in stemming the jobs crisis.
She said it should 'stop peddling about with restrictive pilot schemes'.
Elsewhere, figures from the Department of Finance show that there was an Exchequer deficit of €16.4bn in the first seven months of the year.
Just under €18.7bn was taken in tax receipts, 3% less than the target set out in April's Budget and 17.6% lower than in the same period last year.
A breakdown shows that VAT receipts came in almost €500m below target, as consumer spending continued to be weak.
The take from stamp duty was more than 17% less than what was expected in April.