Pharmaceutical firm Elan has said it is cutting 115 jobs at its Irish operations.
The job losses are part of a ongoing strategic review process, according to the company.
The cuts will be at its 'fill-finished' facility in Athlone and at its biological planning operations in Dublin and Athlone.
Another 115 jobs will go in San Francisco in the US.
Staff are beginning a consultation period with the company over the cuts today.
Last year, the company closed its offices in New York and Tokyo and had indicated more job cuts in its last results announcement.
Elan has a global workforce of 1,700. It employs about one-third of these in Ireland, or 580 people.
