High-risk or critically-ill patients in Sligo General Hospital will be moved to intensive care units in other facilities due to an increase in cases of the micro-organism VRE.
The hospital may also have to defer some elective procedures for a short time as a result.
In a statement the hospital said that the increase of Vancomycin Resistant Enterococci at the intensive care unit was identified as a result of on-going surveillance.
Hospital management believes that the micro-organism is potentially a risk to a small number of patients.
The hospital has, as a precautionary measure, taken the decision to restrict admission to the ICU temporarily.
All elective or planned admissions will be monitored by the hospitals consultant surgeons and consultant anaesthetists on a daily basis according to the statement.
For a short period the hospital may have to defer some elective procedures.