UPC Ireland, the new parent company of cable operator NTL Ireland and Chorus, has said it will be seeking around 350 redundancies from September.
Some job losses had been expected when the two companies merged earlier this year.
A statement from the company said that certain activities currently undertaken by NTL Ireland will be transferred to Chorus and vice versa.
The company added that it may be able to create up to 140 new positions in the future
ATGWU officials have been told the NTL call centre in Waterford city, which employs around 110 people, is expected to close.
The company says that its overall objective is to create a strong national operator for television, internet and telephone services and that a major reorganisation is underway.
The combined workforce of Chorus and NTL Ireland is understood to be around 950.
The primary areas to be affected are customer care, finance, networks and Chorus Sports Channel.
Employees and unions are still in negotiations, and will continue to be until the redundancy process concludes in March 2007.