Trucks carrying food and medical supplies have begun arriving in the parts of Pakistan worst affected by Saturday's earthquake.
With some 2.5 million people left homeless in close to freezing temperatures, there are concerns for those stranded in remote villages.
At least 20,000 people are known to have died but that figure is expected to double.
In Pakistani-run Kashmir at least 17,000 have been killed. In Indian-run Kashmir the death toll stands at around 950. In Pakistan's northwest frontier the death toll stands at 1,600.
Earlier, the Government announced an extra €2 million in aid for Pakistan. The money is in addition to the €1 million announced in the immediate aftermath of the earthquake at the weekend.
The money is to be distributed through non-governmental organisations working in the area.
Speaking on RTÉ Radio’s Morning Ireland, Pakistan's Ambassador to Ireland, Toheed Ahmad, said the scale of the devastation is beyond our imagination.
Mr Ahmad said the immediate need now was to reach the homeless and he appealed for financial aid as his country attempted to deal with the devastation.
It came after tens of thousands of people across mountainous areas of the country spent a second night without shelter in the wake of the disaster.
Officials said 11,000 died in Muzaffarabad, the capital of Pakistan-administered Kashmir.
Many of the victims were school children who had just begun classes when school buildings collapsed on top of them.
The town of Balakot was almost totally destroyed. Pakistan's Interior Minister Aftab Sherpao said attempts to reach Balakot have been hampered by the inaccessible terrain and the weather.
Irish aid agencies launch appeals
Irish aid agencies have launched public appeals for funds to aid the victims of the Pakistan earthquake.
Donations can be given to GOAL by post to GOAL, PO Box 19, Dún Laoghaire, Co Dublin or by telephone to 01-2809779.
The Irish Red Cross is appealing for public donations to Callsave 1850 50 70 70 or online at www.redcross.ie.
Concern can be contacted at Freepost, Camden St, Dublin 2, or on 1850 410 510.
