Silver Ghost will tell the story of motoring pioneer Lord John Douglas-Scott Montagu of Beaulieu, his wife Cis and his secret love affair with his secretary and mistress, Eleanor Velasco Thornton.
It also tells of his connection and friendships with Rolls-Royce founders Charles Rolls and Henry Royce and British artist and sculptor Charles Sykes.
Velasco Thornton was the inspiration for the iconic Spirit of Ecstasy mascot, designed by Sykes, that to this day adorns all Rolls-Royce cars.
Scorsese said: "When I read the story of Silver Ghost, I was mesmerised. I immediately thought: 'This is a picture that has to be made'. And when I was asked to come aboard as a producer alongside Richard Attenborough and Anthony Haas, I didn't hesitate for a moment."
"Martin Scorsese is a giant of the cinema and I am thrilled to be collaborating with Marty and Anthony," said Attenborough.
"What a team to bring this extraordinary story to life... Silver Ghost is a most complex love story, not only between men and women, but men and machines.
"Set at the turn of the last century, it delineates the fascinating story of Charles Rolls and Henry Royce and the highly charged love affairs within the Montagu family."