Kenneth Branagh, Kathryn Thomas, Operation Transformation leaders and Lisa Fallon are among the guests for tonight's Late Late Show.
Oscar-nominated actor and acclaimed director Keneth Branagh will join Ryan from London to talk about his new movie Belfast and will reveal why it is the most personal film he's ever made.
In studio, Ryan will chat to Operation Transformation presenter Kathryn Thomas and this year's leaders, who will share their health goals and plans for 2022.
Also, former head coach with Galway United Lisa Fallon, who took up a top position as a high-performance consultant in FIFA, will tell Ryan about her extraordinary career, being a female in a male-dominated industry and how a serious assault as a young woman shaped her view of the world.
There is also a very special musical performance with Eleanor McEvoy, Mary Black and friends singing Only a Woman's Heart.
Watch The Late Late Show at 9:35pm on RTÉ One and RTÉ Player.