Ryan Tubridy has announced that actor Gabriel Byrne and tenor Andrea Bocelli will be among his guests on the Late Late Show on RTÉ One on Friday night.
Irish screen legend Byrne will discuss the reasons behind writing his revealing autobiography at the age of 70.
Fans of Italian singer Bocelli are promised "a very special performance of a beloved song". There will also be music on the night from The Coronas, who will perform their latest single.
US talk show host Conan O'Brien will be joining the Late Late to discuss "his proud Irish heritage, his hugely successful podcast, and whether Donald Trump is a guest he may want to interview in the future".
Immunologist Professor Luke O'Neill will be in studio to discuss the latest Covid vaccine developments.
Ryan Tubridy will meet Lily Collison to hear about her part in the success of Stripe founders John and Patrick Collison. She will also share how the siblings' younger brother Tommy overcame adversity.
To mark the centenary of Bloody Sunday next weekend, the Late Late studio will be hosting part of Croke Park's museum exhibition. The Bloodied Field author Michael Foley will take viewers through the events of that day and their impact.
The Late Late Show, Friday, RTÉ One, 9:35pm