Miriam O'Callaghan hosts tonight’s Late Late Show, with regular presenter Ryan Tubridy adhering to best practice and staying away from the production due to a persistent cough.
"I'm delighted to be able to step in tonight and present the Late Late Show," O’Callaghan said.
"We have to keep the show on the road. Best wishes to Ryan."
This isn't the first time the show has had a stand-in host, but it certainly is a special edition of the long-running chat show.
This week's edition of The Late Late Show pays tribute to the men and women of Ireland's National Frontline Services who have been bravely leading the fight to slow down and treat the spread of Coronavirus.
Following what promises to be a very special opening segment at the top of the show, viewers around the country will be invited to join in a collective round of applause for our frontline service heroes.
Also on Friday's show, global superstar Hozier will launch an emergency on-air appeal for the ISPCC who are experiencing an upsurge in calls to Childline.
Hozier will perform an exclusive set, live in studio, and promote a new initiative between ISPCC and RTÉ 2FM, where top Irish artists are performing across 2FM every night for a fortnight to raise funds.
Caroline O'Sullivan from the ISPCC will be there with helpful advice for parents who are dealing with children affected by the current situation.
Lee Duffy, a young, fit and healthy League of Ireland footballer, will talk about about his harrowing experience when he contracted Coronavirus and was hospitalised.
Luckily, Lee has now made a full recovery and will be in studio to issue a plea to the young people of Ireland to heed warnings regarding social gatherings.
Mrs Brown's Boys stars Brendan O'Carroll and wife Jennifer Gibney will be talking via Skype link from Florida, and comedian Dara Ó Briain will join the show from London.
Former Irish Rugby International Brian O'Driscoll will also be on tomorrow's show, as well as legendary GAA commentator Mícheál Ó Muircheartaigh.
All of this, plus more, only on The Late Late Show, RTÉ One, Friday at 9.35pm