Baltimore Ravens quarterback Lamar Jackson is the probable NFL MVP.

But he isn't the most important player in Saturday's AFC divisional playoff game.

Star running back Derrick Henry will be the pivotal player on the field when the visiting Tennessee Titans attempt to upset the Ravens, the top-seeded team in the AFC field.

Henry carried the sixth-seeded Titans to a stellar 20-13 upset of the third-seeded New England Patriots last weekend when he established a franchise playoff record with 182 rushing yards. Eddie George held the old mark of 162, set in the 1999 season against the Indianapolis Colts.

The 26-year-old Henry carried 34 times against the Patriots, and the Baltimore defence is expecting to see a lot of the powerful runner on Saturday.

Ravens cornerback Marlon Humphrey is certainly familiar with Henry's style; they were teammates at Alabama when Henry won the Heisman Trophy in 2015.

"I really think it's going to take all 11 (defenders)," Humphrey told reporters on the difficult task of stopping Henry.

"He's 6'3"’ and he has really elite speed also. He can run people over here and there all the time, but if he gets to the edge, he can really outrun you."

Henry won the NFL rushing title with 1,540 yards and took it up a notch against New England. In fact, Ravens safety Earl Thomas feels some Patriots were fearful of being in Henry's path.

"Guys didn't seem like they were too interested in tackling him," Thomas said.

"So, our mindset is a little different. We're going to try to tackle him. Try to swarm. And we're going to see how it plays out."

The Titans were third in the NFL in rushing (138.9) during the regular season, while Baltimore was fifth (93.4) in defending the run.

Of course, the Ravens run the ball better than anyone - and that includes every team in NFL history after they set a record with 3,296 yards.

Jackson supplies magic and force and rushed for 1,206 yards in the regular season, the most by a quarterback in NFL history. He also passed for 3,127 yards and an NFL-best 36 touchdowns as the Ravens averaged an NFL-leading 33.2 points per game.

"He's from Mars," Titans defensive tackle Jurrell Casey said.

"He's definitely an outer space guy. He's unbelievable. The stuff that he's doing so far this season, it's unreal."

Safety Kevin Byard knows dealing with Jackson will be a major challenge for a defence that allowed an average of 20.7 points during the regular season.

He termed Jackson as a better run-throw quarterback than Michael Vick – the person whose QB rushing-yardage mark Jackson broke.

"I would say he's Vick 2.0," Byard said.

"I was talking to my dad about it (Monday) night. I think he is faster than Vick, and he's so dynamic. I grew up watching Vick and I wanted to wear number seven because of Vick.

"I think kids are growing up now wanting to be just like Lamar Jackson. He is so dynamic and a trailblazer in his own right. And facing him is a big challenge for us.

"I have been watching him all year, making guys look silly out there, so we are going to have to do a good job containing this guy."

Titans quarterback Ryan Tannehill will never be compared to Jackson when it comes to foot speed, but he will be looking to improve to 2-0 as a postseason starter.

He didn't have to do much throwing against New England, with Henry running wild, and was 8-of-15 passing for 72 yards with one touchdown and one interception.

Naturally, Tannehill's long gainer was a 22-yarder to Henry.

And it's no secret the Titans plan to give the ball to Henry over and over and over against Baltimore.

"He has a certain skillset, with size and strength and speed and durability - those are all great qualities for a running back in January," Tennessee coach Mike Vrabel said.

"So he'll do everything that he has to to get ready and to do whatever it is that we ask him to do in the gameplan."

Baltimore's top running back doesn't appear to be in the same condition. Mark Ingram II suffered a calf injury in Week 16 and aggravated it during last week's bye, and he is listed as questionable, although the Ravens are hopeful he will feature.

Ravens coach John Harbaugh wasn't thrilled with questions pertaining to Ingram, who rushed for 1,018 yards and 10 touchdowns during a stellar regular season.

"We're not talking about injuries this week," Harbaugh insisted.

"We'll just wait and see. You'll know on Saturday on all those guys."

Tight end Mark Andrews (ankle) also is questionable for the Ravens.

Tennessee linebacker Jayon Brown (shoulder) was ruled out for the game on Thursday. He twice left the victory over Patriots due to the injury.

Adam Humphries (ankle) was ruled out while fellow receiver Cody Hollister (ankle) is questionable.

Baltimore Ravens v Tennessee Titans, M&T Bank Stadium, 1.15am