Joey Carbery has been preferred to Jack Crowley at out-half for Munster's interprovincial derby against Connacht on Saturday.
Crowley, who made his first Ireland start in last weekend’s win over Australia, has been named among the replacements.
Tadhg Beirne makes his 50th Munster appearance while fellow Ireland internationals Peter O’Mahony and Craig Casey also return to the starting line-up, with Antoine Frisch handed his first BKT United Rugby Championship start.
Jean Kleyn partners Beirne in the second row after recovering from a rib injury.
Munster head coach Graham Rowntree has named six forwards on the bench including Jeremy Loughman, Gavin Coombes and Edwin Edogbo.
Connacht also welcome back the majority of their Ireland contingent with Bundee Aki making his first start of the season.
Dave Heffernan, Finlay Bealham and Cian Prendergast come into the pack, where Josh Murphy partners Gavin Thornbury in the second row.
Mack Hansen misses out with a thigh injury while Tiernan O’Halloran is also sidelined, so John Porch switches to full-back and Byron Ralston starts on the wing.
Caolin Blade and captain Jack Carty form the half-back combination while Aki partners Tom Farrell in midfield as Connacht chase a fourth win in five games against Munster.
Connacht have also opted for a six-two split on the bench, with Kieran Marmion and Conor Fitzgerald providing backline cover.
Munster: Mike Haley; Calvin Nash, Antoine Frisch, Rory Scannell, Shane Daly; Joey Carbery, Craig Casey; Josh Wycherley, Diarmuid Barron, Roman Salanoa; Jean Kleyn, Tadhg Beirne; Peter O'Mahony (capt), John Hodnett, Alex Kendellen
Replacements: Niall Scannell, Jeremy Loughman, John Ryan, Edwin Edogbo, Jack O’Donoghue, Paddy Patterson, Jack Crowley, Gavin Coombes
Connacht: John Porch; Ryron Ralston, Tom Farrell, Bundee Aki, Alex Wooton; Jack Carty, Caolin Blade; Denis Buckley, Dave Heffernan, Finlay Bealham; Josh Murphy, Gavin Thornbury; Cian Prendergast, Conor Olvier, Jarrad Butler
Replacements: Shane Delahunt, Peter Dooley, Jack Aungier, Niall Murphy, Oisín Dowling, Kieran Marmion, Conor Fitzgerald, Paul Boyle
Leinster welcome Rónan Kelleher back from injury for Saturday’s game against Glasgow Warriors at the RDS, live on RTÉ1 and RTÉ Player, while Harry Byrne could make his first appearance of the season.
Kelleher has recovered from the hamstring problem that saw him miss Ireland’s autumn Tests and packs down between Ed Byrne and Thomas Clarkson in the front row.
Joe McCarthy, who made his Ireland debut in the win over Australia, partners Ross Molony in the second row, with Scott Penny and Max Deegan joining captain Rhys Ruddock in the back row.
Ross Byrne, who came off the bench to kick the winning penalty for Ireland against the Wallabies, resumes his half-back partnership with Luke McGrath while Charlie Ngatai and Liam Turner are named in midfield.
Ryan Baird and Byrne are named among the replacements after returning to full training this week.
Leinster: Jamie Osborne; Rob Russell, Liam Turner, Charlie Ngatai, Dave Kearney; Ross Byrne, Luke McGrath; Ed Byrne, Rónan Kelleher, Thomas Clarkson; Ross Molony, Joe McCarthy; Rhys Ruddock (capt), Scott Penny, Max Deegan
Replacements: John McKee, Michael Milne, Vakh Abdaladze, Jason Jenkins, Ryan Baird, Cormac Foley, Harry Byrne, Chris Cosgrave
Watch Leinster v Glasgow Warriors (Saturday, 3.15pm) live on RTÉ1 and RTÉ Player, or listen commentary on Saturday Sport on RTÉ Radio 1.
Listen to live commentary of Munster v Connacht (Saturday, 7.35pm) on RTÉ Radio 1 Extra.