Leinster and Connacht's Heineken Champions Cup last-16 second leg will take place at the Aviva Stadium.
The EPCR has revealed the dates and kick-off times for their Round of 16 matches in April, with the most notable detail being the venue of the all-Irish knockout game.
The four-time champions have traditionally played home quarter-finals and semi-finals at the Aviva Stadium, but had been due to stage last season's last-16 tie with Toulon at the RDS, before it was eventually cancelled due to Covid-19.
And with an Irish derby against Connacht set to draw a crowd far larger than the 18,500 capacity RDS, Leinster have decided to move their home leg to the 51,700 Aviva.
That second leg will take place at the Aviva on Friday 15 April [Good Friday], with a 5.30pm kick-off, while their first leg at the Sportsground will take place a week earlier, 8 April, at 8pm.
Munster and Ulster will both play their Round of 16 matches on Saturdays, with Munster's away leg against the Exeter Chiefs given top billing on 9 April with a 5.30pm kick-off, before their return leg at Thomond Park on Saturday 16 April at 3pm.
Ulster's away game against Toulouse has also been moved to a larger venue, with Toulouse bringing their home tie to the city's 33,150 capacity 'Le Stadium', rather than their traditional Stade Ernest-Wallon.
They'll kick off at 3.15pm [Irish time] on Saturday 9 April, while Ulster's home leg at Kingspan Stadium on Saturday 16 April will get under way at 8pm.
Heineken Champions Cup - Round of 16 first leg
Friday 8 April
Connacht v Leinster, The Sportsground, 8pm
Saturday 9 April
Sale Sharks v Bristol Bears, AJ Bell Arena, 1pm
Union Bordeaux-Bègles v Stade Rochelais, venue TBC, 1pm
Stade Toulousain v Ulster, Le Stadium, 3.15pm
Exeter Chiefs v Munster, Sandy Park 5.30pm
Stade Francais Paris v Racing 92, Stade Jean Bouin, 5.30pm
Sunday 10 April
Montpellier Hérault v Harlequins, GGL Stadium, 1pm
ASM Clermont Auvergne v Leicester Tigers, Stade Marcel-Michelin, 3.15pm
Round of 16 second leg
Friday 15 April
Leinster v Connacht, Aviva Stadium, 5.30pm
Bristol Bears v Sale Sharks, Ashton Gate, 8pm
Saturday 16 April
Harlequins v Montpellier Hérault, Twickenham Stoop, 12.30pm
Munster v Exeter Chiefs, Thomond Park, 3pm
Stade Rochelais v Union Bordeaux-Bégles, Stade Marcel Deflandre, 3pm
Leicester Tigers v ASM Clermont Auvergne, Mattioli Woods Welford Road, 5.30pm
Ulster v Stade Toulousain, Kingspan Stadium, 8pm
Sunday 17 April
Racing 92 v Stade Francais Paris, Paris La Défense Arena, 3.30pm