Mona McSharry finished seventh in the European Championships 50m breaststroke final in Rome.
McSharry, who had come into the final as the seventh fastest swimmer, was unable to improve on her qualifying time after a long week of action.
The 21-year-old got off to a decent start but was unable to rein in the leading group and eventually finished in a time of 31.15.
Ruta Meilutyte of Lithuania took the victory in a time of 29.59, adding European to the World Championship gold she won in the same event back in July.
A controversial figure, Meilutyte returned to competitive action last December, having served out a two-year suspension for missing three anti-doping tests.
Local favourite Benedetta Pilato claimed silver for Italy, while Great Britain's Imogen Clark won the bronze.
Tanya Watson and Ciara McGing put on a fine display as the pair competed in the Platform Final, a first international final for McGing and the first time Ireland was represented by two divers in an international final.
McGing's best score of the five dives came in her opening dive, inward 2 ½ somersaults for 63 points, while Watson saved her best for last, scoring 64 points for a back 2 ½ somersaults 1 ½ twists.
Tokyo semi-finalist Watson finished the higher of the pair with a season’s best 285.55 points with McGing scoring 279.30 points.
Gold went to Great Britain's Andrea Spendolini Siriex (333.60) with Sophia Lysku (329.80) of Ukraine and Christina Wassen (314.10) of Germany completing the podium.