Scott McTominay's second-minute goal was enough to give Napoli a 1-0 victory over Cagliari in Serie A, while Udinese defeated Genoa 2-0.
Lens returned to the top of the Ligue 1 table with a 5-1 victory over Angers.
Goals from Florian Thauvin, Odsonne Edouard and Mamadou Sangare put the hosts three up at half-time, and Edouard added a fourth three minutes into the second period.
Lanroy Machine pulled one back but Matthieu Udol netted Lens’ fifth to move them two points clear of Paris St Germain, who face Nice on Saturday.
Villarreal climbed to third in La Liga thanks to a 3-1 victory over Real Sociedad.
The Yellow Submarine flew out of the traps and were three up inside 23 minutes through Gerard Moreno, Georges Mikautadze and Nicolas Pepe before Luka Sucic pulled one back.
RB Leipzig pulled level on points with fellow Champions League chasers Hoffenheim after thumping their rivals 5-0 in the Bundesliga, with Brajan Gruda and Christoph Baumgartner both scoring twice in the first half.
