Valencia gave themselves some breathing space at the bottom of La Liga after a 1-0 win over Osasuna.
Largie Ramazani's penalty midway through the second half was enough to settle a tense affair.
Victory moves Los Che five points clear of the bottom three.
Elche drew 2-2 with Espanyol, who finished with 10 men, and Celta Vigo were 2-1 winners at Girona. Real Betis and Sevilla also drew 2-2.
Federico Gatti scored a stoppage-time equaliser as Juventus came from 3-1 down to draw 3-3 with Roma in Serie A.
Evan Ndicka and Donyell Malen put Roma 3-1 up after Wesley Franca’s opener was cancelled out by Francisco Conceicao, but Jeremie Boga cut the deficit before late substitute Gatti had the final say.
AC Milan left it late to strengthen their reopen their four-point cushion ahead of Napoli in second place.
An 89th-minute strike from Strahinja Pavlovic and Rafael Leao’s goal in the fourth minute of added time saw off Cremonese 2-0.
The victory sees them sit 10 points behind city rivals Inter ahead of next weekend’s San Siro derby.
Atalanta missed the chance to move into the European positions after they were beaten 2-1 by 10-man Sassuolo.
The hosts were reduced to 10 men in the 16th minute when Andrea Pinamonti saw red but went 2-0 up through Ismael Kone and Kristian Thorstvedt. Yunus Musah got one back near the end but it was a poor result for Atalanta.
Stuttgart moved level on points with third-placed Hoffenheim in the Bundesliga after a 4-0 win over Wolfsburg.
Frankfurt beat Freiburg 2-0 to keep their European ambitions alive while RB Leipzig beat Hamburg 2-1.
In Ligue 1 Pierre-Emerick Aubameyang scored two late goals as Marseille earned a first win under Habib Beye, beating Lyon 3-2.
OM lost 2-0 at Brest in Beye’s first game in charge last week and it was not looking good as Corentin Tolisso’s third-minute goal and Remi Himbert’s strike in the 76th minute put Lyon 2-1 up at the Stade Velodrome.
Igor Paixao had earlier levelled for the hosts but it was the former Arsenal striker who stepped up, equalising in the 81st minute and then winning it in the first minute of injury time.
There were also wins for Paris FC, Lille and Brest while Lorient and Auxerre drew.
