Bukayo Saka's stunner wrapped up England's comprehensive win against Wales as Thomas Tuchel's side built on last month's impressive victory in Serbia.
The German head coach sparked debate by leaving out star names such as Jude Bellingham and Phil Foden to stick with the squad that ended September's camp with a five-star display in Belgrade.
Tuchel's decision paid dividends as England started where they left off in Serbia, with Morgan Rogers, Ollie Watkins and Saka goals meaning Wales were down for the count just 20 minutes into Thursday's Wembley friendly.
Craig Bellamy said in the build-up that a boxing promoter would not match the team fourth in FIFA's world rankings against his 30th-placed side and Watkins should have added a fourth before half-time.
The striker, who started with skipper Harry Kane out injured, collided with a post as he attempted to score and had to be replaced at the break.
Wales can take heart from an improved second-half display as Bellamy's men turn their attention to Monday's crunch World Cup qualifier against Belgium.
A trip to Latvia, and perhaps early qualification, awaits Tuchel's side after England won their eighth successive meeting with Wales.
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