Attention turns to the fight to avoid relegation in the Premier Division tonight, while Bohemians look to make ground on leaders Shamrock Rovers.
With a reduced schedule due to clubs in European action, just two matches will take place on the quietest Friday night of the campaign.
Shelbourne, the Hoops, St Patrick's Athletic and Drogheda United all had their games brought forward to facilitate games in Europe, although the move proved a needless exercise.
One of the most important matches of the year will be held in the RSC as a floundering Cork City make the short journey to Waterford.
Both sides are at something of a low ebb, as the home side shipped seven goals last week in Derry.
For City, their next three matches against the Blues, Sligo Rovers and Galway United are crucial.
Having fallen five points behind Sligo, Ger Nash is in desperate need of a first victory as City boss as he takes charge of an eighth league game.
Waterford, for their part, are in danger of being sucked towards the play-off if their poor run continues.
The capitulation in Derry was alarming, with manager John Coleman declaring the honeymoon is over for him since taking over.
A new signing was made as Liverpudlian Finlay Armstrong joined this week.
Coleman threatened to make dramatic changes to his squad if performances like in Derry were repeated.
Victory in the game would go a long way to dispelling notions of a relegation fight, so there is so much riding on the match for both teams.
Bohs welcome Galway United to Dalymount Park knowing they can't afford any slip-ups.
Currently 11 points behind the leaders, the Gypsies will be determined to solidfy their top three spot more than anything else.
After 21 matches without a draw, two have come along for Bohs in the last fortnight.
Galway have lost ground on the top half with a latest defeat in Drogheda compounding disappointing form recently.
They have had just two away wins all year, but one did come in Dalymount Park as now former player Moses Dyer scored a memorable goal.
Bohs boss Alan Reynolds is hoping to demonstrate the progress made by his side since that game when they do battle with the Tribesmen.
He said:: "We all recognise the importance of this game. It's important we start strongly and set the tempo of the game."Galway are a very capable side. They came up here earlier in the season and won, and it took everything from us to beat them when we played them away too.
"It’s one of our games in hand on the teams that are competing in Europe this week so we really want to make it count. "We’re at home, it’s yet another sold-out home crowd at Dalymount Park so we want to feed off that energy again."