Leeds United will take on AC Milan at Aviva Stadium in a pre-season friendly on Saturday, 9 August.
It will be Leeds' final friendly before their return to the Premier League a week later.
The fixture will serve as an international date for Milan ahead of the Serie A season, which is set to kick off on the weekend of 23 August.
It will be the first time the two sides have met since the UEFA Champions League group stages in the 2000/2001 season, having only ever met three times in all competitions previously.
Leeds, who return to Dublin after nine years, have had many Irish internationals pass through their ranks in the form of John Giles, Robbie Keane, Ian Harte and Gary Kelly.
Kelly, who played 462 times for Leeds and amassed 52 caps for Republic of Ireland commented: "It’s going to be an exciting game and certainly a great test for this Leeds side before their Premier League campaign kicks off.
"I have great memories of the last time we played Milan, captaining the side against them in the Champions League.
"Obviously as a proud Irishman I am delighted this fixture is coming to Dublin, which I know the locals will welcome, packing out the Aviva Stadium and creating a great atmosphere."
The game kicks off at 3pm.
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