Republic of Ireland striker Tom Cannon helped Stoke City beat Sunderland 2-1 at the Stadium of Light to book their place in the FA Cup fourth round.
Mark Robins' side made the perfect start when Cannon scored an early penalty, before Sunderland substitute Milan Aleksic levelled 19 minutes into the second half.
Sunderland, who introduced Enzo Le Fee to the supporters before kick-off after the midfielder completed his loan move from Roma on Friday night, looked the more likely side to score a winner in normal time.
But Niall Ennis pounced on a Sunderland defensive mix-up to score the winner with eight minutes of extra-time remaining.
Morgan Whittaker dumped Premier League Brentford out of the cup as Sky Bet Championship strugglers Plymouth made light of life without Wayne Rooney.
Whittaker's 82nd-minute effort handed bottom-of-the-table Argyle, with new boss Miron Muslic looking on, a 1-0 win at the Gtech Community Stadium to extend their unbeaten run since Rooney's departure to three games.
Tosin Adarabioyo scored in both halves as Premier League Chelsea brushed aside League Two strugglers Morecambe 5-0 with Christopher Nkunku atoning for his penalty miss with a 50th-minute strike before Joao Felix found the back of the net twice in quick succession to wrap up a comfortable win.
Dango Ouattara's double helped ease Bournemouth to a 5-1 over West Brom with Jason Kluivert, Antoine Semenyo and substitute Daniel Jebbison also scoring after Caleb Taylor had headed the visitors in front.
Jamie Vardy celebrated his 38th birthday with a successful penalty as top-flight Leicester routed QPR 6-2.
James Justin's double, coupled with goals from Stephy Mavididi, Facundo Buonanotte, Vardy and Wout Faes, sent the hosts through, although Jonathan Varane and Rayan Kolli briefly dragged it back to 3-2.
Goals from Ryan Yates and Ramon Sosa saw high-flying Nottingham Forest progress with the minimum of fuss despite making 11 changes courtesy of a 2-0 home win over Luton.
Georginio Rutter helped himself to a double before Julio Enciso and substitute Solly March wrapped up a comfortable 4-0 win for Brighton at Norwich.
Rayan Ait-Nouri and Rodrigo Gomes fired Premier League Wolves to a 2-1 win at Bristol City, for whom Scott Twine replied with a superb free-kick, while Andreas Weimann scored the only goal to give Blackburn a 1-0 win at Sky Bet Championship rivals Middlesbrough.
Winger Ayumu Yokoyama scored League One leaders Birmingham's fastest FA Cup goal as they beat Lincoln 2-1, Lyndon Dykes doubling their advantage before Jovon Makama converted a stoppage-time penalty.
Two goals from Demetri Mitchell and a third from Vincent Harper saw League One Exeter reach round four for the first time in 44 years after a 3-1 win over Championship Oxford. The visitors led through Matt Phillips' goal but finished with 10 men after Tyler Goodrham was sent off nine minutes from time.
Largie Ramazani's second-half header sealed Leeds United a 1-0 win and ensured they avoided an upset against Yorkshire rivals Harrogate.
Last season's semi-finalists Coventry booked their place in the fourth round of this year’s competition with a penalty shootout victory over Sheffield Wednesday following a 1-1 draw after extra time.
Liam Kitching’s first-half goal was cancelled out by Anthony Musaba’s stoppage-time equaliser before the Sky Blues prevailed 4-3 in the shootout.
In the early kick-off, Trent Alexander-Arnold led from the front as Liverpool eased into the fourth round with a 4-0 victory over Accrington Stanley. Diogo Jota, Jayden Danns and Federico Chiesa were also on the mark at Anfield.
