Egypt suffered more Africa Cup of Nations shoot-out heartache as goalkeeper Lionel Mpasi scored the winning penalty to send DR Congo through to the quarter-finals.
All four of the Pharaohs' knockout games in the 2021 tournament required additional time, culminating in a spot-kick defeat to Senegal in the final.
And, after a 1-1 draw following extra-time, they went the same way in San Pedro with an 8-7 loss on penalties.
Mostafa Mohamed continued to step up in the absence of the injured Mohamed Salah with his fourth goal in as many matches from the spot, cancelling out Meschack Elia's opener, with Egypt hanging on in extra time following Mohamed Hamdy's 97th-minute red card.
Mohamed missed from 12 yards the second time around and keeper Mohamed Abou Gabal also fluffed his lines, leaving opposite number Mpasi to hold his nerve and set up a last-eight clash with Guinea, who scored a last-gasp winner in 1-0 win over 10-man Equatorial Guinea.
Mohamed Bayo was the match winner in a poor-quality game looked destined for extra time in Abidjan before Bayo headed home from Ibrahim Diakite's cross with just 22 seconds remaining in the last of eight minutes of stoppage time.
The majority of that time had come from a lengthy VAR check which eventually saw Equatorial Guinea awarded a penalty for a foul by Sekou Sylla on Iban Salvador, only for captain Emilio Nsue to hit the base of a post with his spot-kick.