Champions Peamount United suffered just their second league defeat of their season as they lost 3-0 to Galway United.
After a goalless first half in Drom, Galway took control in the second half to earn an impressive victory.
Rola Olusola opening the scoring in the 47th minute with a low finish after being played in on the right and she grabbed her second in the 65th minute.
Any hopes of a Peamount recovery were ended 10 minutes later as Jenna Slattery grabbed Galway's third.
Second-placed Shamrock Rovers were far too strong for Treaty United as they recorded an emphatic 4-1 win on the road.
Rovers dominated the opening period but only led by one goal at half time, Alannah McEvoy pouncing from close range in the 29th minute.
Indeed, Treaty could have been level in the break as Cara Griffin's neat footwork opened up some space, but her shot rebounded off the crossbar.
Aine O’Gorman added a second for Rovers on the restart and they added a third when Joy Ralph’s corner ended up in the net.
O’Gorman blasted into the roof of the net in the 76th minute, with Orlagh Fitzpatrick grabbing a consolation for Treaty late on with the Rovers defence marked absent.
Dublin derby honours belonged to Shelbourne as they recorded a 3-0 win over Bohemians at Tolka Park.
Noel King, who will depart as manager at the end of the season, saw his side make the perfect start as they went ahead in the eighth minute when her chip from distance caught out Medbh Ryan.
The hosts added two in quick succession just before the interval with Christie Gray and Kerri Letmon profiting to all but end the contest by the break.
Bohs were much improved after the interval but Shelbourne comfortably eased to the points.
An early double proved decisive as ninth beat eighth with Sligo Rovers earning a 2-1 home win over DLR Waves.
Casey Howe fired them ahead emphatically after nine minutes having been played through by Fiona Doherty and Jodie Loughrey quickly doubled their advantage with a finish from the edge of the box 18 minutes in.
Waves found a way back into the contest soon after the break when Cliodhna Donnelly scrambled home, but they couldn’t find an equaliser with Ciara Henry going close to adding a third for Sligo at the death with the woodwork denying her.
In Saturday's late game, Athlone move six points clear of Wexford Youths after a 2-1 win.
Athlone were a goal ahead of the break after a fine strike from Dana Scheriff, who controlled beautifully before sliding low to the net in the 23rd minute.
With an FAI Cup final to come, the Athlone players wee keen to impress and they doubled their lead early in the second half, Gillian Keenan on target.
Wexford did improve from there and Nicola Sinnott brought them back into the contest when she headed home midway through the second half, but they couldn't find a leveller.
