Substitute Aaron Connolly scored a late brace as Hull came from behind to beat 10-man Blackburn 2-1 in a breathless encounter.
Rovers were up against it from the 17th minute when Harry Pickering was given his marching orders for upending Liam Delap when clean through but displayed great resilience and managed to take a 74th-minute lead through Sam Gallagher.
However, Hull recovered superbly and Connolly volleyed home an 81st-minute equaliser before handing the Tigers their first away league win since January with a composed finish seven minutes later.
Hull deserved their second straight victory on the balance of play but Rovers perhaps should have come out of the game with something and will rue missed chances for Gallagher and Niall Ennis a minute before Connolly's decisive strike.
Southampton made it consecutive away victories after Che Adams scored a dramatic stoppage-time winner to claim a 2-1 success over Plymouth at Home Park.
Nathan Tella opened the scoring just after the break but they were immediately pegged back when Ryan Hardie turned home from close range.
But in stoppage time, Adam Armstrong’s goal-bound header was parried by Conor Hazard into the path of Adams who scored to maintain the Saints’ unbeaten start to the season.
Ipswich maintained their 100% start on their return to the Championship with a 1-0 win over QPR.
The Tractor Boys left it until the 75th minute to get the breakthrough as Conor Chaplin scored at the second attempt.
Debutant Cesare Casadei came off the bench and netted a stoppage-time winner to earn Leicester a 2-1 victory over Cardiff.
Wanya Marcal-Madivadua’s first-half strike was cancelled out by Aaron Ramsey’s sublime effort just before the interval which looked like earning Cardiff a share of the spoils.
But on-loan Chelsea midfielder Casadei kept up Leicester’s 100% start to the campaign before Cardiff had defender Mahlon Romeo sent off late on.
Goals from Koji Miyoshi and Lukas Jutkiewicz helped Birmingham to a 2-0 win over Bristol City, who played the last 15 minutes with 10 men after Robert Dickie received a second booking.
Preston maintained their unbeaten start to the league campaign as Liam Lindsay’s header earned a 1-0 win over Sheffield Wednesday, who are the only team in the division without a point.
Andre Vidigal scored his fourth goal of the season as Stoke bounced back to winning ways with a 1-0 home win over Watford.
Swansea and Coventry drew 1-1 in Wales.
Matty Godden netted the opener for the visitors in the 39th minute but Swans drew level just two minutes later when summer signing Jerry Yates nodded home his second goal in as many home appearances.
Jobe Bellingham scored either side of half-time as Sunderland came from behind to record their first win of the season with a 2-1 win over Rotherham.
Huddersfield and Middlesbrough are both still looking for their first league wins of the campaign after they played out a 1-1 draw at the Riverside Stadium.
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