Manchester United will face record six-time winners Sevilla in the Europa League quarter-finals.
Erik ten Hag's side won 1-0 in Seville on Thursday night to see off Real Betis and reach the last eight.
The Red Devils will be at home first and, if they progress, they will face either Juventus or Sporting - who beat Arsenal on penalties on Thursday night.
Meanwhile, in the quarter-finals of the Europa Conference League, West Ham will face a Gent team which was grouped with Shamrock Rovers earlier in the competition.
David Moyes' side are struggling in the Premier League but have enjoyed a fine European campaign and will be aiming to reach a semi-final for the second year running.
The Hammers were eliminated in the last four of the Europa League last season and will face either Anderlecht or AZ Alkmaar if they can get past Gent.
Europa League quarter-final draw
Manchester United v Sevilla
Juventus v Sporting
Bayer Leverkusen v Union Saint-Gilloise
Feyenoord v AS Roma
* Team drawn first hosts the first leg
* First legs: 13 April
* Second legs: 20 April
Semi-final draw
Semi-final 1: Juventus/Sporting v United/Sevilla
Semi-final 2: Feyenoord/Roma v Leverkusen/Union
* Team drawn first hosts the first leg
* First legs: 11 May
* Second legs: 18 May
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