Chelsea will face holders Real Madrid in a daunting Champions League quarter-final, while Pep Guardiola will have a reunion with former employers Bayern Munich with Manchester City pitted against the Bundesliga giants.
Madrid, who dispatched Liverpool in some style in the last round, will face the Blues for the second season running in the knockout stages.
Last season they knocked the Premier League side out at the quarter-final stage 5-4 after extra time in the return leg at the Bernabeu.
Graham Potter's side saw off Borussia Dortmund to reach the last eight.
Bayern, who failed to win Europe's top prize during Guardiola's three-year stint in charge will have home advantage for the second leg of their tie with free-scoring and unbeaten Manchester City.
If both Chelsea and City progress, they will meet in the semi-final - a repeat of the 2021 final which Chelsea won 1-0.
In the other quarter-finals, Inter will face Benfica, while it's an all-Italian clash when Napoli face AC Milan
The quarter-final first legs will be on 11/12 April and the second legs on 18/19 April, with all of the Tuesday night action live on RTÉ.
Watch Derry City v Sligo Rovers in the League of Ireland live on Friday from 7.35pm on RTÉ2 and RTÉ Player.