Ex-Bohs man Promise Omochere struck a memorable winner to send Fleetwood into the fourth round of the FA Cup for the first time with a 2-1 win at home to QPR.
Fleetwood had to come from behind but Omochere rifled in midway through the second half to knock the Sky Bet Championship side out.
Sam Field had broken the deadlock for QPR on 37 minutes, bundling in after Lyndon Dykes had helped on Ilias Chair's ball into the box.
But the lead lasted three minutes as the unmarked Toto Nsiala headed in Danny Andrew's corner to draw Fleetwood level.
And in the 67th minute Omochere - who moved from Bohs to Fleetwood last summer produced a fine finish on the turn to give Fleetwood a deserved win and create one of the shocks of the third round.
Republic of Ireland midfielder Alan Browne wrapped up a 3-1 victory for Preston North End, who secured their spot in the fourth round for the first time since 2018 thanks to a win over Huddersfield at Deepdale.
The contest was brought to life by two quickfire scrappy goals just before the hour mark.
Preston failed to clear their lines from a routine corner and Sorba Thomas again showed his prowess from out wide as his drilled cross was slammed home by debutant Florian Kamberi.
That setback stirred Preston into immediate action as Ben Woodburn's teasing cross into the box bounced off Huddersfield skipper Tom Lees for a bizarre own goal equaliser.
Just as the game looked set to drift off to a draw, and a replay in West Yorkshire, Bambo Diaby showed his talents in the opposition box for Preston. A deep free-kick was not dealt with by the Huddersfield defence and Diaby kept his composure to smash an unstoppable volley home in the 73rd minute.
Huddersfield's chances of another win on the road at Deepdale ended five minutes from time when Browne pounced on some slack defending by Kaine Kesler-Hayden to force home a low cross and wrap up Preston's place in the next round.
A severely depleted Watford side made a tame exit when they lost 2-0 at fellow Sky Bet Championship play-off chasers Reading, for whom Shane Long was on target.
Watford showed little in a scrappy first half, with Reading going ahead in stoppage time direct from a Kelvin Abrefa cross that evaded goalkeeper Maduka Okoye.
Reading dominated much of the second period and sealed the victory late on - again in stoppage time - when Long scampered clear to slot home.
Kelechi Iheanacho extended his fine FA Cup record by firing Leicester into the fourth round with the second-half winner in a 1-0 victory at Sky Bet League Two strugglers Gillingham.
Striker Iheanacho claimed his 16th career goal in the competition as the 2021 winners avoided a major upset at the expense of the club languishing at the bottom of the English Football League.
Layvin Kurzawa and Daniel James secured Fulham's place in the hat at the expense of Hull as Marco Silva gained victory over his former employers.
Kurzawa was one of seven changes to Premier League Fulham's line-up and was left with a simple 37th-minute finish after Matt Ingram parried Harry Wilson's shot, while James secured a 2-0 win at the death.
Ireland striker Aaron Connolly came on as 61st-minute sub for Hull but could not haul his new team back into the contest.
Brandon Thomas-Asante struck in the third minute of stoppage time to salvage a 3-3 draw for West Brom against National League side Chesterfield.
The first meeting between the two clubs since 1948 turned out to be an absolute thriller as the Spireites twice came from behind at the Technique Stadium to lead through Armando Dobra's double.
But just when it looked as though they would hold out for a famous victory against a team 66 league places above them, Thomas-Asante broke their hearts at the death to earn a replay for the Championship visitors.
Said Benrahma struck against his former club Brentford as West Ham put their Premier League struggles to one side with a 1-0 win.
Benrahma, prised from the Bees for £30m three years ago, climbed off the bench to provide the only moment of quality in a dour third-round encounter.
The Algerian winger fired home from 25 yards before opting not to celebrate against the side he spent two and a half years with.
For West Ham at least there was a measure of revenge for the 2-0 Premier League defeat inflicted by Brentford eight days earlier.
Ross Stewart and Luke O'Nien scored in stoppage time as Sunderland snatched a dramatic 2-1 victory over stunned Shrewsbury.
Matthew Pennington looked to have sealed a memorable win for Steve Cotterill's side against their Championship opponents with nine minutes to go.
But the highly-rated Stewart levelled in the second minute of added time.
And then, with deflated Shrewsbury settling for a replay at the Stadium of Light, they were undone again as O'Nien pounced two minutes later to send the Black Cats through.
Daniel Jebbison and Jayden Bogle opened their accounts for the season as Sheffield United eased past Millwall 2-0 at The Den.
Former Shamrock Rovers defender Andy Lyons and Ireland international CJ Hamilton both impressed as Blackpool belied their poor Championship form to hammer Premier League outfit Nottingham Forest 4-1.
Non-league Boreham Wood are also in the pot for the fourth-round draw after they fought back to draw 1-1 against Accrington and earn a replay.
League One promotion hopefuls Ipswich beat Rotherham 4-1 at Portman Road, where Conor Chaplin and Wes Burns both scored second-half penalties.
Gavin Bazunu was between the posts as Southampton marched on with a 2-1 victory over Crystal Palace at Selhurst Park.
Tottenham's Harry Kane moved to within one goal of the club's record scorer Jimmy Greaves with the only goal in the win over Portsmouth.
