Miguel Almiron struck twice as Newcastle cruised to a comfortable 4-1 victory over 10-man Fulham at Craven Cottage.
Newcastle went into the game with just one win in the Premier League this campaign, but stormed to an impressive victory following an eighth-minute red card for Nathaniel Chalobah.
Callum Wilson put Newcastle ahead just after Fulham were reduced to 10 men, before Almiron scored his first of the afternoon with a stunning volley from the edge of the penalty area.
Sean Longstaff then added Newcastle's third just before half-time, with Almiron capping off a dominant Magpies performance with a fourth in the 57th minute.
Fulham grabbed a late consolation goal, as Newcastle's standards slipped at the back, with Bobby De Cordova-Reid heading home from close range.
Shane Duffy was an unused substitute for the home side.
Everton claimed only their second Premier League away win of 2022 as goals from Conor Coady and Dwight McNeil inspired a 2-1 victory at Southampton.
Joe Aribo put the Saints ahead following a lacklustre first half at St Mary's, but Frank Lampard's visitors hit back instantly, with Coady and McNeil scoring in the space of three second-half minutes.
It helped the Toffees extend their unbeaten run to six matches and provided a rare success on the road, a victory at Leicester having been Everton's only previous away win in the top flight this calendar year.
Republic of Ireland captain Seamus Coleman skippered Everton as he started in the absence of Scottish international Nathan Patterson.
Bournemouth were left fuming to be denied a penalty amid a 0-0 Premier League grind with Brentford.
The Cherries were left perplexed by rookie referee Thomas Bramall ruling out a spot-kick despite being ordered to the pitchside monitors by VAR official John Brooks.
The Vitality Stadium hosts felt frustrated to see Kristoffer Ajer's wayward sliding challenge on Jordan Zemura go unpunished.
Bramall took charge in the Premier League for just the second time, and his move to stick with his original onfield decision of no penalty was met with clear derision by the Cherries.
Bournemouth's ire grew still further at the final whistle, as Bramall gave no second thought to the ball striking Mathias Jensen's arm in the area.
The last-gasp skirmish should not have yielded a penalty, but Bramall struggled to control the situation as the Cherries players surrounded him.
These two teams proved too tame to topple the other on the English south coast in the end, with killer instinct conspicuous by its absence in Dorset.