Jayson Molumby, on loan from Brighton, gave West Brom the lead at Middlesbrough, but Chris Wilder's side fought back for a 2-1 victory to prevent Steve Bruce from enjoying his first success as Baggies boss.
Andy Carroll's low ball into the six-yard box on 28 minutes was half cleared as far as Molumby, with the Republic of Ireland international firing into the bottom corner of the net for his first goal for the club.
It was a deserved lead for the visitors at the Riverside, who ended a 479-minute goal drought stretching back to 22 January.
Other than the complaints about a few decisions, Boro had little to shout about in the opening period and were unable to test Baggies keeper Sam Johnstone or show signs of levelling before the break.
West Brom looked the better of the two in the early exchanges after the restart too, so Wilder introduced Duncan Watmore and Andraz Sporar to his forward line.
The move instantly lifted the hosts and six minutes later they were level, when Paddy McNair slid in to convert Marcus Tavernier's low cross into the area after a sublime through-ball from the impressive Riley McGree.
Boro were in command from that moment on, the home support were lifted and the winner seemed inevitable.
It arrived nine minutes later. Anfernee Dijksteel and Isaiah Jones superbly created the opening, with the latter's low ball to the back post finding Tavernier to fire beyond Johnstone for his first goal since September.
Wilder's tactical changes had worked and a ninth league win from his 15 matches in charge of Middlesbrough was achieved - with Aaron Connolly featuring from the off.
Reading interim boss Paul Ince marked his return to management with a 2-1 home win over Birmingham.
The 54-year-old former Manchester United and England midfielder - whose son Tom is on loan at the Royals from Stoke - was handed the reins on Saturday evening just hours after Veljko Paunovic's departure following a 3-2 win at Preston.
Lucas Joao broke the deadlock in the 67th minute, with John Swift converting a second from the penalty spot with 15 minutes left.
A late own goal from Royals defender Tom McIntyre set up a tense finale, but Ince's men held out to move further clear of the Sky Bet Championship relegation zone.
Bottom club Barnsley finally got their first away win of the season after beating Hull 2-0.
Midfielder Callum Styles gave the Tykes the lead in the 24th minute and Carlton Morris added a second in stoppage-time at the end of the first half.
Barnsley move to within a point of Peterborough and Derby after a second victory in three Championship games.
Viktor Gyokeres struck with a minute left to give Coventry a 2-1 win at Bristol City, edging them to within two points of the top six.
Ian Maatsen put the Sky Blues ahead in the 25th minute at Ashton Gate.
Bristol frontman Antoine Semenyo crashed a header against the crossbar early in the second half, before Chris Martin nodded in an equaliser from a well-worked free-kick just after the hour.
Gyokeres, though, secured all three points with a breakaway goal in the 89th minute.
Elsewhere, it finished goalless between Preston and Nottingham Forest at Deepdale.
